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However, simulations based on this network structure could not match the experimental data for aa stimulation alone (Supplementary Fig. 3b) which was particularly evident for AMPK (AMPK pT172, TSC2 pS1387), IRS/PI3K (Akt pT308), Akt (PRAS40 pT246) and mTORC2 (Akt pS473).cheap nfl jerseys The quality of the fit between this model and our data reported a value of 1,415 using the Akaike information criterion (AIC)27 (Table 1, single aa input).
Conclusions The choice of time domain (Stratus) vsspectra domain (Cirrus) OCT systems has a measurable impact on clinical decision making in exudative AMD. Spectral domain OCT systems may be able to generate more consensus in clinical interpretation and, in particular cases, detect disease activity not detected by time domain systems. Clinical trials using OCT based clinical evaluations of exudative AMD may need to account for these inter system differences in planning and analysis..
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